Pathophysiology of Coronary Collaterals

Pathophysiology of Coronary Collaterals#

While the existence of structural adaptation of coronary anastomoses is undisputed, the potential of coronary collaterals to be capable of functional adaptation has been questioned. For many years, collateral vessels were thought to be rigid tubes allowing only limited blood flow governed by the pressure gradient across them. This concept was consistent with the notion that although collaterals...

Determinants of Human Coronary Collaterals

The human coronary collateral circulation is prognostically relevant. The understanding of collateral formation and its determinants may guide future therapeutic strategies aiming at promoting collateral growth and functionality, and hence reducing the global burden of coronary artery disease (CAD).

Cannabis, Collaterals, and Coronary Occlusion

A 51-year-old gentleman, who regularly smoked cannabis, presented with chest pain and diaphoresis. He was haemodynamically stable. ECG showed ST depression, inferiorly, and 1 mm ST elevation in lead aVR. Emergent coronary angiography showed thrombotic occlusion of the left main coronary artery (LMCA), the dominant RCA provided Rentrop grade II collaterals to the LAD. The LMCA was successfully r...

The functional importance of coronary collaterals.

Regression and reappearance of coronary collaterals.

KHOURI, EDWARD M., DONALD E. GREGG, AND GEORGE M. MCGRANAHAN, JR. Regression and reappearance of coronary collaterals. Am. J. Physiol. 220(3) : 655-661. 1971 .-The regression of the coronary collateral circulation after an occlusion is removed and its ability to develop again following reocclusion was studied in two groups of dogs. In one group the first occlusion of the circumflex branch of th...